| 1 | |  MFK Tatran Liptovsky Mikulas | 28 | 18 | 6 | 4 | 55 | 26 | 29 | 60 | G18:00 | 15/05/21 | R 29  MSK Puchov 0 MFK Tatran Liptovsky Mikulas 2 G18:00 | 08/05/21 | R 28 FK Slavoj Trebisov 0 MFK Tatran Liptovsky Mikulas 2 G18:00 | 01/05/21 | R 27 MFK Tatran Liptovsky Mikulas 2 FK Poprad 0 B17:30 | 24/04/21 | R 26 MSK Zilina B 2 MFK Tatran Liptovsky Mikulas 2 B17:30 | 17/04/21 | R 25 MFK Tatran Liptovsky Mikulas 1 FK Zeleziarne Podbrezova 1 M17:00 | 10/04/21 | R 24 MFK Skalica 3 MFK Tatran Liptovsky Mikulas 0 |
| 2 | |  MFk Dukla Banska Bystrica | 27 | 17 | 5 | 5 | 69 | 36 | 33 | 56 | B18:00 | 15/05/21 | R 29 KFC Komarno 1 MFk Dukla Banska Bystrica 1 B18:00 | 08/05/21 | R 28 MFk Dukla Banska Bystrica 1 FC STK 1914 Samorin 1 M18:00 | 02/05/21 | R 27 Partizan Bardejov 3 MFk Dukla Banska Bystrica 1 G17:30 | 24/04/21 | R 26 MFk Dukla Banska Bystrica 2 FK Kosice 0 G17:00 | 10/04/21 | R 24 MFk Dukla Banska Bystrica 4 MSK Puchov 1 M17:00 | 03/04/21 | R 23 MFK Tatran Liptovsky Mikulas 1 MFk Dukla Banska Bystrica 0 |
| 3 | |  FK Zeleziarne Podbrezova | 27 | 16 | 5 | 6 | 56 | 24 | 32 | 53 | G18:00 | 15/05/21 | R 29 Partizan Bardejov 0 FK Zeleziarne Podbrezova 1 B18:00 | 08/05/21 | R 28 FK Zeleziarne Podbrezova 0 FK Kosice 0 G17:30 | 24/04/21 | R 26 FK Zeleziarne Podbrezova 4 MSK Puchov 2 B17:30 | 21/04/21 | R 22 FK Slavoj Trebisov 3 FK Zeleziarne Podbrezova 3 B17:30 | 17/04/21 | R 25 MFK Tatran Liptovsky Mikulas 1 FK Zeleziarne Podbrezova 1 G17:00 | 10/04/21 | R 24 FK Zeleziarne Podbrezova 4 FK Poprad 0 |
| 4 | |  MFK Skalica | 27 | 15 | 7 | 5 | 52 | 30 | 22 | 52 | G18:00 | 15/05/21 | R 29 FC STK 1914 Samorin 1 MFK Skalica 2 G18:00 | 08/05/21 | R 28 MFK Skalica 1 Partizan Bardejov 0 M18:00 | 01/05/21 | R 27 FK Kosice 1 MFK Skalica 0 B17:30 | 17/04/21 | R 25 MSK Puchov 1 MFK Skalica 1 G17:00 | 10/04/21 | R 24 MFK Skalica 3 MFK Tatran Liptovsky Mikulas 0 G17:00 | 03/04/21 | R 23 FK Poprad 2 MFK Skalica 4 |
| 5 | |  FK Kosice | 27 | 15 | 3 | 9 | 39 | 26 | 13 | 48 | B18:00 | 21/05/21 | R 30 FK Poprad 1 FK Kosice 1 G18:00 | 15/05/21 | R 29 FK Kosice 1 MSK Zilina B 0 B18:00 | 08/05/21 | R 28 FK Zeleziarne Podbrezova 0 FK Kosice 0 G18:00 | 01/05/21 | R 27 FK Kosice 1 MFK Skalica 0 M17:30 | 24/04/21 | R 26 MFk Dukla Banska Bystrica 2 FK Kosice 0 G17:30 | 17/04/21 | R 25 FK Kosice 5 FK Dubnica Nad Vahom 0 |
| 6 | |  FC STK 1914 Samorin | 27 | 12 | 4 | 11 | 40 | 33 | 7 | 40 | M18:00 | 15/05/21 | R 29 FC STK 1914 Samorin 1 MFK Skalica 2 B18:00 | 08/05/21 | R 28 MFk Dukla Banska Bystrica 1 FC STK 1914 Samorin 1 G11:30 | 02/05/21 | R 27 FC STK 1914 Samorin 3 FK Dubnica Nad Vahom 0 G17:00 | 23/04/21 | R 26 Slovan Bratislava B 0 FC STK 1914 Samorin 1 G11:30 | 18/04/21 | R 25 FC STK 1914 Samorin 3 Artmedia Petrzalka 1 G17:00 | 10/04/21 | R 24 KFC Komarno 1 FC STK 1914 Samorin 3 |
| 7 | |  KFC Komarno | 27 | 11 | 5 | 11 | 29 | 39 | -10 | 38 | B18:00 | 15/05/21 | R 29 KFC Komarno 1 MFk Dukla Banska Bystrica 1 M18:00 | 08/05/21 | R 28 FK Dubnica Nad Vahom 3 KFC Komarno 0 G18:00 | 01/05/21 | R 27 KFC Komarno 3 Slovan Bratislava B 2 G11:30 | 25/04/21 | R 26 Artmedia Petrzalka 1 KFC Komarno 3 G17:30 | 17/04/21 | R 25 KFC Komarno 2 FK Slavoj Trebisov 1 M17:00 | 10/04/21 | R 24 KFC Komarno 1 FC STK 1914 Samorin 3 |
| 8 | |  MSK Puchov | 27 | 11 | 4 | 12 | 38 | 43 | -5 | 37 | M18:00 | 15/05/21 | R 29 MSK Puchov 0 MFK Tatran Liptovsky Mikulas 2 G18:00 | 08/05/21 | R 28 FK Poprad 3 MSK Puchov 5 G18:00 | 02/05/21 | R 27 MSK Puchov 1 MSK Zilina B 0 M17:30 | 24/04/21 | R 26 FK Zeleziarne Podbrezova 4 MSK Puchov 2 B17:30 | 17/04/21 | R 25 MSK Puchov 1 MFK Skalica 1 M17:00 | 10/04/21 | R 24 MFk Dukla Banska Bystrica 4 MSK Puchov 1 |
| 9 | |  FK Slavoj Trebisov | 27 | 9 | 7 | 11 | 45 | 46 | -1 | 34 | M18:00 | 15/05/21 | R 29 Slovan Bratislava B 2 FK Slavoj Trebisov 1 M18:00 | 08/05/21 | R 28 FK Slavoj Trebisov 0 MFK Tatran Liptovsky Mikulas 2 G11:30 | 02/05/21 | R 27 Artmedia Petrzalka 0 FK Slavoj Trebisov 3 G17:30 | 24/04/21 | R 26 FK Slavoj Trebisov 3 FK Poprad 0 B17:30 | 21/04/21 | R 22 FK Slavoj Trebisov 3 FK Zeleziarne Podbrezova 3 M17:30 | 17/04/21 | R 25 KFC Komarno 2 FK Slavoj Trebisov 1 |
| 10 | |  Artmedia Petrzalka | 27 | 9 | 7 | 11 | 35 | 40 | -5 | 34 | B18:00 | 15/05/21 | R 29 Artmedia Petrzalka 1 FK Dubnica Nad Vahom 1 M11:30 | 08/05/21 | R 28 Slovan Bratislava B 2 Artmedia Petrzalka 1 M11:30 | 02/05/21 | R 27 Artmedia Petrzalka 0 FK Slavoj Trebisov 3 M11:30 | 25/04/21 | R 26 Artmedia Petrzalka 1 KFC Komarno 3 M11:30 | 18/04/21 | R 25 FC STK 1914 Samorin 3 Artmedia Petrzalka 1 G11:30 | 11/04/21 | R 24 Artmedia Petrzalka 3 Partizan Bardejov 2 |
| 11 | |  MSK Zilina B | 27 | 8 | 6 | 13 | 53 | 47 | 6 | 30 | M18:00 | 15/05/21 | R 29 FK Kosice 1 MSK Zilina B 0 M18:00 | 02/05/21 | R 27 MSK Puchov 1 MSK Zilina B 0 B17:30 | 24/04/21 | R 26 MSK Zilina B 2 MFK Tatran Liptovsky Mikulas 2 G17:30 | 17/04/21 | R 25 FK Poprad 1 MSK Zilina B 6 M17:00 | 10/04/21 | R 24 FK Slavoj Trebisov 3 MSK Zilina B 1 M11:30 | 04/04/21 | R 23 MSK Zilina B 1 FK Zeleziarne Podbrezova 2 |
| 12 | |  FK Dubnica Nad Vahom | 27 | 7 | 9 | 11 | 27 | 37 | -10 | 30 | B18:00 | 15/05/21 | R 29 Artmedia Petrzalka 1 FK Dubnica Nad Vahom 1 G18:00 | 08/05/21 | R 28 FK Dubnica Nad Vahom 3 KFC Komarno 0 M11:30 | 02/05/21 | R 27 FC STK 1914 Samorin 3 FK Dubnica Nad Vahom 0 B17:30 | 24/04/21 | R 26 FK Dubnica Nad Vahom 2 Partizan Bardejov 2 M17:30 | 17/04/21 | R 25 FK Kosice 5 FK Dubnica Nad Vahom 0 G17:00 | 03/04/21 | R 23 MSK Puchov 0 FK Dubnica Nad Vahom 1 |
| 13 | |  Partizan Bardejov | 27 | 6 | 10 | 11 | 27 | 38 | -11 | 28 | M18:00 | 15/05/21 | R 29 Partizan Bardejov 0 FK Zeleziarne Podbrezova 1 M18:00 | 08/05/21 | R 28 MFK Skalica 1 Partizan Bardejov 0 G18:00 | 02/05/21 | R 27 Partizan Bardejov 3 MFk Dukla Banska Bystrica 1 B17:30 | 24/04/21 | R 26 FK Dubnica Nad Vahom 2 Partizan Bardejov 2 G12:00 | 17/04/21 | R 25 Partizan Bardejov 2 Slovan Bratislava B 1 M11:30 | 11/04/21 | R 24 Artmedia Petrzalka 3 Partizan Bardejov 2 |
| 14 | |  Slovan Bratislava B | 27 | 7 | 0 | 20 | 32 | 69 | -37 | 21 | G18:00 | 15/05/21 | R 29 Slovan Bratislava B 2 FK Slavoj Trebisov 1 G11:30 | 08/05/21 | R 28 Slovan Bratislava B 2 Artmedia Petrzalka 1 M18:00 | 01/05/21 | R 27 KFC Komarno 3 Slovan Bratislava B 2 M17:00 | 23/04/21 | R 26 Slovan Bratislava B 0 FC STK 1914 Samorin 1 M12:00 | 17/04/21 | R 25 Partizan Bardejov 2 Slovan Bratislava B 1 M15:30 | 10/04/21 | R 24 Slovan Bratislava B 0 FK Kosice 4 |
| 15 | |  FK Poprad | 27 | 3 | 0 | 24 | 24 | 87 | -63 | 9 | B18:00 | 21/05/21 | R 30 FK Poprad 1 FK Kosice 1 M18:00 | 08/05/21 | R 28 FK Poprad 3 MSK Puchov 5 M18:00 | 01/05/21 | R 27 MFK Tatran Liptovsky Mikulas 2 FK Poprad 0 M17:30 | 24/04/21 | R 26 FK Slavoj Trebisov 3 FK Poprad 0 M17:30 | 17/04/21 | R 25 FK Poprad 1 MSK Zilina B 6 M17:00 | 10/04/21 | R 24 FK Zeleziarne Podbrezova 4 FK Poprad 0 |
