| 1 | |  Almeria | 42 | 24 | 9 | 9 | 68 | 35 | 33 | 81 | B21:00 | 29/05/22 | R 42  Leganes 2 Almeria 2 B23:00 | 21/05/22 | R 41 Almeria 1 Alcorcon 1 G22:00 | 13/05/22 | R 40 Real Sociedad San Sebastian B 0 Almeria 2 G19:15 | 07/05/22 | R 39 Almeria 3 SD Amorebieta 0 G21:30 | 30/04/22 | R 38 Burgos 0 Almeria 2 G22:00 | 25/04/22 | R 37 Almeria 1 Sporting de Gijon 0 |
| 2 | |  Real Valladolid | 42 | 24 | 9 | 9 | 71 | 43 | 28 | 81 | G21:00 | 29/05/22 | R 42 Real Valladolid 3 Huesca 0 G23:00 | 21/05/22 | R 41 UD Ibiza 1 Real Valladolid 2 G19:15 | 14/05/22 | R 40 Real Valladolid 2 SD Ponferradina 0 G17:00 | 08/05/22 | R 39 Eibar 0 Real Valladolid 2 M22:00 | 02/05/22 | R 38 Real Valladolid 1 Real Sociedad San Sebastian B 2 G17:15 | 24/04/22 | R 37 CD Mirandes 0 Real Valladolid 1 |
| 3 | |  Eibar | 42 | 23 | 11 | 8 | 61 | 45 | 16 | 80 | M21:00 | 29/05/22 | R 42 Alcorcon 1 Eibar 0 G23:00 | 21/05/22 | R 41 Eibar 2 Tenerife 0 G22:00 | 14/05/22 | R 40 Leganes 2 Eibar 3 M17:00 | 08/05/22 | R 39 Eibar 0 Real Valladolid 2 |
| 4 | |  Las Palmas | 42 | 19 | 13 | 10 | 57 | 47 | 10 | 70 | G21:00 | 29/05/22 | R 42 Sporting de Gijon 0 Las Palmas 1 G23:00 | 21/05/22 | R 41 Las Palmas 2 Real Oviedo 1 G15:00 | 15/05/22 | R 40 Alcorcon 0 Las Palmas 2 G22:00 | 06/05/22 | R 39 Las Palmas 1 CD Mirandes 0 |
| 5 | |  Tenerife | 42 | 20 | 9 | 13 | 53 | 37 | 16 | 69 | M21:00 | 29/05/22 | R 42 Tenerife 1 Cartagena 2 M23:00 | 21/05/22 | R 41 Eibar 2 Tenerife 0 M22:00 | 15/05/22 | R 40 Tenerife 0 Malaga 2 |
| 6 | |  Girona | 42 | 20 | 8 | 14 | 57 | 42 | 15 | 68 | B21:00 | 29/05/22 | R 42 Burgos 0 Girona 0 G23:00 | 21/05/22 | R 41 Girona 2 CD Mirandes 0 M17:00 | 15/05/22 | R 40 Sporting de Gijon 2 Girona 1 |
| 7 | |  Real Oviedo | 42 | 17 | 17 | 8 | 57 | 41 | 16 | 68 | G21:00 | 29/05/22 | R 42 Real Oviedo 3 UD Ibiza 2 M23:00 | 21/05/22 | R 41 Las Palmas 2 Real Oviedo 1 B22:00 | 16/05/22 | R 40 Real Oviedo 3 Real Zaragoza 3 B19:15 | 07/05/22 | R 39 Malaga 0 Real Oviedo 0 G17:00 | 30/04/22 | R 38 Real Oviedo 3 CD Mirandes 0 G15:00 | 24/04/22 | R 37 Alcorcon 1 Real Oviedo 2 |
| 8 | |  SD Ponferradina | 42 | 17 | 12 | 13 | 57 | 55 | 2 | 63 | M19:15 | 28/05/22 | R 42 SD Amorebieta 1 SD Ponferradina 0 M23:00 | 21/05/22 | R 41 SD Ponferradina 0 Leganes 3 M19:15 | 14/05/22 | R 40 Real Valladolid 2 SD Ponferradina 0 G22:00 | 07/05/22 | R 39 SD Ponferradina 3 Burgos 1 G19:15 | 01/05/22 | R 38 SD Ponferradina 4 Cartagena 2 G17:15 | 23/04/22 | R 37 CF Fuenlabrada 2 SD Ponferradina 3 |
| 9 | |  Cartagena | 42 | 18 | 6 | 18 | 63 | 57 | 6 | 60 | G21:00 | 29/05/22 | R 42 Tenerife 1 Cartagena 2 G21:00 | 21/05/22 | R 41 Cartagena 5 SD Amorebieta 0 B17:00 | 14/05/22 | R 40 Burgos 1 Cartagena 1 B15:00 | 08/05/22 | R 39 Cartagena 0 Leganes 0 M19:15 | 01/05/22 | R 38 SD Ponferradina 4 Cartagena 2 G17:15 | 23/04/22 | R 37 Cartagena 3 Girona 0 |
| 10 | |  Real Zaragoza | 42 | 12 | 20 | 10 | 39 | 46 | -7 | 56 | G22:00 | 27/05/22 | R 42 Real Sociedad San Sebastian B 1 Real Zaragoza 2 G22:00 | 20/05/22 | R 41 Real Zaragoza 1 Lugo 0 B22:00 | 16/05/22 | R 40 Real Oviedo 3 Real Zaragoza 3 M19:15 | 08/05/22 | R 39 Real Zaragoza 0 Alcorcon 3 M19:15 | 30/04/22 | R 38 Eibar 2 Real Zaragoza 0 B19:30 | 24/04/22 | R 37 Real Zaragoza 0 Burgos 0 |
| 11 | |  Burgos | 42 | 15 | 10 | 17 | 41 | 41 | 0 | 55 | B21:00 | 29/05/22 | R 42 Burgos 0 Girona 0 G21:00 | 21/05/22 | R 41 Malaga 0 Burgos 1 B17:00 | 14/05/22 | R 40 Burgos 1 Cartagena 1 M22:00 | 07/05/22 | R 39 SD Ponferradina 3 Burgos 1 M21:30 | 30/04/22 | R 38 Burgos 0 Almeria 2 B19:30 | 24/04/22 | R 37 Real Zaragoza 0 Burgos 0 |
| 12 | |  Leganes | 42 | 13 | 15 | 14 | 50 | 51 | -1 | 54 | B21:00 | 29/05/22 | R 42 Leganes 2 Almeria 2 G23:00 | 21/05/22 | R 41 SD Ponferradina 0 Leganes 3 M22:00 | 14/05/22 | R 40 Leganes 2 Eibar 3 B15:00 | 08/05/22 | R 39 Cartagena 0 Leganes 0 G19:30 | 02/05/22 | R 38 Leganes 2 Huesca 1 B19:30 | 24/04/22 | R 37 Lugo 0 Leganes 0 |
| 13 | |  Huesca | 42 | 13 | 15 | 14 | 49 | 44 | 5 | 54 | M21:00 | 29/05/22 | R 42 Real Valladolid 3 Huesca 0 G21:00 | 21/05/22 | R 41 Huesca 3 Real Sociedad San Sebastian B 2 M15:00 | 14/05/22 | R 40 SD Amorebieta 1 Huesca 0 B17:00 | 07/05/22 | R 39 Huesca 1 Sporting de Gijon 1 M19:30 | 02/05/22 | R 38 Leganes 2 Huesca 1 B22:00 | 22/04/22 | R 37 Tenerife 0 Huesca 0 |
| 14 | |  CD Mirandes | 42 | 15 | 7 | 20 | 58 | 62 | -4 | 52 | G22:00 | 27/05/22 | R 42 CD Mirandes 5 CF Fuenlabrada 1 M23:00 | 21/05/22 | R 41 Girona 2 CD Mirandes 0 G17:00 | 15/05/22 | R 40 CD Mirandes 4 UD Ibiza 0 M22:00 | 06/05/22 | R 39 Las Palmas 1 CD Mirandes 0 M17:00 | 30/04/22 | R 38 Real Oviedo 3 CD Mirandes 0 M17:15 | 24/04/22 | R 37 CD Mirandes 0 Real Valladolid 1 |
| 15 | |  UD Ibiza | 42 | 12 | 16 | 14 | 53 | 59 | -6 | 52 | M21:00 | 29/05/22 | R 42 Real Oviedo 3 UD Ibiza 2 M23:00 | 21/05/22 | R 41 UD Ibiza 1 Real Valladolid 2 M17:00 | 15/05/22 | R 40 CD Mirandes 4 UD Ibiza 0 B19:15 | 08/05/22 | R 39 UD Ibiza 1 Lugo 1 G17:00 | 01/05/22 | R 38 Sporting de Gijon 0 UD Ibiza 1 B17:15 | 24/04/22 | R 37 UD Ibiza 1 Las Palmas 1 |
| 16 | |  Lugo | 42 | 10 | 20 | 12 | 46 | 52 | -6 | 50 | G19:15 | 28/05/22 | R 42 Lugo 1 Malaga 0 M22:00 | 20/05/22 | R 41 Real Zaragoza 1 Lugo 0 M17:00 | 14/05/22 | R 40 Lugo 1 CF Fuenlabrada 3 B19:15 | 08/05/22 | R 39 UD Ibiza 1 Lugo 1 M19:15 | 01/05/22 | R 38 Lugo 0 Tenerife 2 B19:30 | 24/04/22 | R 37 Lugo 0 Leganes 0 |
| 17 | |  Sporting de Gijon | 42 | 11 | 13 | 18 | 43 | 48 | -5 | 46 | M21:00 | 29/05/22 | R 42 Sporting de Gijon 0 Las Palmas 1 B21:00 | 21/05/22 | R 41 CF Fuenlabrada 0 Sporting de Gijon 0 G17:00 | 15/05/22 | R 40 Sporting de Gijon 2 Girona 1 B17:00 | 07/05/22 | R 39 Huesca 1 Sporting de Gijon 1 M17:00 | 01/05/22 | R 38 Sporting de Gijon 0 UD Ibiza 1 M22:00 | 25/04/22 | R 37 Almeria 1 Sporting de Gijon 0 |
| 18 | |  Malaga | 42 | 11 | 12 | 19 | 36 | 57 | -21 | 45 | M19:15 | 28/05/22 | R 42 Lugo 1 Malaga 0 M21:00 | 21/05/22 | R 41 Malaga 0 Burgos 1 G22:00 | 15/05/22 | R 40 Tenerife 0 Malaga 2 B19:15 | 07/05/22 | R 39 Malaga 0 Real Oviedo 0 M23:00 | 29/04/22 | R 38 Las Palmas 2 Malaga 1 M19:30 | 23/04/22 | R 37 Malaga 1 Eibar 3 |
| 19 | |  SD Amorebieta | 42 | 9 | 16 | 17 | 44 | 63 | -19 | 43 | G19:15 | 28/05/22 | R 42 SD Amorebieta 1 SD Ponferradina 0 M21:00 | 21/05/22 | R 41 Cartagena 5 SD Amorebieta 0 G15:00 | 14/05/22 | R 40 SD Amorebieta 1 Huesca 0 M19:15 | 07/05/22 | R 39 Almeria 3 SD Amorebieta 0 G15:00 | 01/05/22 | R 38 SD Amorebieta 2 CF Fuenlabrada 1 M15:00 | 23/04/22 | R 37 Real Sociedad San Sebastian B 2 SD Amorebieta 1 |
| 20 | |  Real Sociedad San Sebastian B | 42 | 10 | 10 | 22 | 43 | 61 | -18 | 40 | M22:00 | 27/05/22 | R 42 Real Sociedad San Sebastian B 1 Real Zaragoza 2 M21:00 | 21/05/22 | R 41 Huesca 3 Real Sociedad San Sebastian B 2 M22:00 | 13/05/22 | R 40 Real Sociedad San Sebastian B 0 Almeria 2 G17:00 | 07/05/22 | R 39 CF Fuenlabrada 1 Real Sociedad San Sebastian B 2 G22:00 | 02/05/22 | R 38 Real Valladolid 1 Real Sociedad San Sebastian B 2 G15:00 | 23/04/22 | R 37 Real Sociedad San Sebastian B 2 SD Amorebieta 1 |
| 21 | |  CF Fuenlabrada | 42 | 6 | 15 | 21 | 39 | 65 | -26 | 33 | M22:00 | 27/05/22 | R 42 CD Mirandes 5 CF Fuenlabrada 1 B21:00 | 21/05/22 | R 41 CF Fuenlabrada 0 Sporting de Gijon 0 G17:00 | 14/05/22 | R 40 Lugo 1 CF Fuenlabrada 3 M17:00 | 07/05/22 | R 39 CF Fuenlabrada 1 Real Sociedad San Sebastian B 2 M15:00 | 01/05/22 | R 38 SD Amorebieta 2 CF Fuenlabrada 1 M17:15 | 23/04/22 | R 37 CF Fuenlabrada 2 SD Ponferradina 3 |
| 22 | |  Alcorcon | 42 | 6 | 11 | 25 | 37 | 71 | -34 | 29 | G21:00 | 29/05/22 | R 42 Alcorcon 1 Eibar 0 B23:00 | 21/05/22 | R 41 Almeria 1 Alcorcon 1 M15:00 | 15/05/22 | R 40 Alcorcon 0 Las Palmas 2 G19:15 | 08/05/22 | R 39 Real Zaragoza 0 Alcorcon 3 M17:00 | 01/05/22 | R 38 Alcorcon 0 Girona 1 M15:00 | 24/04/22 | R 37 Alcorcon 1 Real Oviedo 2 |
