| 1 | |  Veres Rivne | 29 | 20 | 5 | 4 | 54 | 20 | 34 | 65 | G16:00 | 05/06/21 | R 29  Veres Rivne 5 FC Avangard Kramatorsk 1 G19:00 | 31/05/21 | R 1 FC Obolon Kiev 0 Veres Rivne 2 M19:00 | 25/05/21 | R 28 Volyn Lutsk 2 Veres Rivne 1 B17:00 | 21/05/21 | R 27 Veres Rivne 3 FC Alians Lypova Dolyna 3 M18:00 | 16/05/21 | R 26 FC Metalist 1925 4 Veres Rivne 1 G17:00 | 12/05/21 | R 6 FC VPK-Agro Shevchenkivka 0 Veres Rivne 4 |
| 2 | |  FC Chornomorets Odessa | 29 | 17 | 7 | 5 | 43 | 22 | 21 | 58 | M17:30 | 05/06/21 | R 29 FC Chornomorets Odessa 0 FC Alians Lypova Dolyna 2 G19:00 | 27/05/21 | R 28 FC Metalist 1925 0 FC Chornomorets Odessa 1 G19:00 | 21/05/21 | R 27 FC Chornomorets Odessa 4 Krystal Kherson 0 M16:00 | 15/05/21 | R 26 Agrobiznes Volochisk 1 FC Chornomorets Odessa 0 B16:00 | 07/05/21 | R 25 MFC Mykolaiv 1 FC Chornomorets Odessa 1 G15:00 | 30/04/21 | R 24 PFC Nyva Ternopil 0 FC Chornomorets Odessa 1 |
| 3 | |  FC Metalist 1925 | 29 | 16 | 8 | 5 | 35 | 20 | 15 | 56 | G17:30 | 05/06/21 | R 29 MFC Kremin Kremenchuk 0 FC Metalist 1925 4 M19:00 | 27/05/21 | R 28 FC Metalist 1925 0 FC Chornomorets Odessa 1 G16:00 | 21/05/21 | R 27 FC Prykarpattya Ivano-Frankivsk 0 FC Metalist 1925 3 G18:00 | 16/05/21 | R 26 FC Metalist 1925 4 Veres Rivne 1 B17:00 | 08/05/21 | R 25 FC Obolon Kiev 1 FC Metalist 1925 1 G15:00 | 29/04/21 | R 24 FC Metalist 1925 3 FC Hirnyk-Sport Horishni Plavni 2 |
| 4 | |  MFC Mykolaiv | 29 | 15 | 7 | 7 | 48 | 22 | 26 | 52 | M17:30 | 05/06/21 | R 29 MFC Mykolaiv 0 FC Polissya 1 G17:00 | 30/05/21 | R 4 MFC Mykolaiv 2 Volyn Lutsk 1 G17:00 | 26/05/21 | R 28 MFC Mykolaiv 4 PFC Nyva Ternopil 0 G17:00 | 21/05/21 | R 27 MFC Mykolaiv 1 FC VPK-Agro Shevchenkivka 0 G17:00 | 15/05/21 | R 26 MFC Mykolaiv 2 MFC Kremin Kremenchuk 0 B16:00 | 07/05/21 | R 25 MFC Mykolaiv 1 FC Chornomorets Odessa 1 |
| 5 | |  Agrobiznes Volochisk | 29 | 15 | 6 | 8 | 45 | 26 | 19 | 51 | M17:30 | 05/06/21 | R 29 PFC Nyva Ternopil 1 Agrobiznes Volochisk 0 M18:00 | 26/05/21 | R 28 Agrobiznes Volochisk 1 FC VPK-Agro Shevchenkivka 2 G17:00 | 21/05/21 | R 27 MFC Kremin Kremenchuk 0 Agrobiznes Volochisk 1 G16:00 | 15/05/21 | R 26 Agrobiznes Volochisk 1 FC Chornomorets Odessa 0 M16:00 | 07/05/21 | R 25 FC Prykarpattya Ivano-Frankivsk 2 Agrobiznes Volochisk 1 G16:00 | 03/05/21 | R 1 Agrobiznes Volochisk 3 FC Polissya 2 |
| 5 | |  FC Obolon Kiev | 1 | 1 | 0 | 0 | 4 | 1 | 3 | 3 | |
| 6 | |  FC Alians Lypova Dolyna | 29 | 14 | 8 | 7 | 45 | 30 | 15 | 50 | G17:30 | 05/06/21 | R 29 FC Chornomorets Odessa 0 FC Alians Lypova Dolyna 2 G18:00 | 26/05/21 | R 28 FC Alians Lypova Dolyna 4 FC Prykarpattya Ivano-Frankivsk 1 B17:00 | 21/05/21 | R 27 Veres Rivne 3 FC Alians Lypova Dolyna 3 G16:00 | 16/05/21 | R 26 FC Alians Lypova Dolyna 1 FC Obolon Kiev 0 G18:00 | 12/05/21 | R 7 FC Alians Lypova Dolyna 4 FC Polissya 2 G16:00 | 07/05/21 | R 25 FC Hirnyk-Sport Horishni Plavni 2 FC Alians Lypova Dolyna 3 |
| 7 | |  Volyn Lutsk | 29 | 13 | 7 | 9 | 38 | 26 | 12 | 46 | M17:30 | 05/06/21 | R 29 FC Prykarpattya Ivano-Frankivsk 2 Volyn Lutsk 0 M17:00 | 30/05/21 | R 4 MFC Mykolaiv 2 Volyn Lutsk 1 G19:00 | 25/05/21 | R 28 Volyn Lutsk 2 Veres Rivne 1 M18:00 | 21/05/21 | R 27 FC Obolon Kiev 2 Volyn Lutsk 1 G15:00 | 16/05/21 | R 26 Volyn Lutsk 2 FC Hirnyk-Sport Horishni Plavni 0 G17:00 | 12/05/21 | R 14 Volyn Lutsk 2 FC Prykarpattya Ivano-Frankivsk 0 |
| 8 | |  FC Obolon Kiev | 28 | 11 | 4 | 13 | 40 | 33 | 7 | 37 | M17:30 | 05/06/21 | R 29 FC Obolon Kiev 0 FC Hirnyk-Sport Horishni Plavni 1 M19:00 | 31/05/21 | R 1 FC Obolon Kiev 0 Veres Rivne 2 G17:00 | 26/05/21 | R 28 FC Avangard Kramatorsk 1 FC Obolon Kiev 2 G18:00 | 21/05/21 | R 27 FC Obolon Kiev 2 Volyn Lutsk 1 M16:00 | 16/05/21 | R 26 FC Alians Lypova Dolyna 1 FC Obolon Kiev 0 B17:00 | 08/05/21 | R 25 FC Obolon Kiev 1 FC Metalist 1925 1 |
| 9 | |  FC Hirnyk-Sport Horishni Plavni | 28 | 10 | 5 | 13 | 39 | 43 | -4 | 35 | G17:30 | 05/06/21 | R 29 FC Obolon Kiev 0 FC Hirnyk-Sport Horishni Plavni 1 M18:00 | 26/05/21 | R 28 FC Polissya 3 FC Hirnyk-Sport Horishni Plavni 2 M17:30 | 21/05/21 | R 27 FC Hirnyk-Sport Horishni Plavni 0 FC Avangard Kramatorsk 2 M15:00 | 16/05/21 | R 26 Volyn Lutsk 2 FC Hirnyk-Sport Horishni Plavni 0 M16:00 | 07/05/21 | R 25 FC Hirnyk-Sport Horishni Plavni 2 FC Alians Lypova Dolyna 3 M15:00 | 29/04/21 | R 24 FC Metalist 1925 3 FC Hirnyk-Sport Horishni Plavni 2 |
| 10 | |  FC Polissya | 29 | 9 | 8 | 12 | 31 | 35 | -4 | 35 | G17:30 | 05/06/21 | R 29 MFC Mykolaiv 0 FC Polissya 1 G18:00 | 26/05/21 | R 28 FC Polissya 3 FC Hirnyk-Sport Horishni Plavni 2 M18:00 | 21/05/21 | R 27 PFC Nyva Ternopil 2 FC Polissya 0 M17:00 | 16/05/21 | R 26 FC Polissya 1 FC Avangard Kramatorsk 2 M18:00 | 12/05/21 | R 7 FC Alians Lypova Dolyna 4 FC Polissya 2 B17:00 | 07/05/21 | R 25 FC VPK-Agro Shevchenkivka 0 FC Polissya 0 |
| 11 | |  FC VPK-Agro Shevchenkivka | 29 | 10 | 4 | 15 | 28 | 47 | -19 | 34 | M17:30 | 05/06/21 | R 29 FC VPK-Agro Shevchenkivka 1 Krystal Kherson 2 G18:00 | 26/05/21 | R 28 Agrobiznes Volochisk 1 FC VPK-Agro Shevchenkivka 2 M17:00 | 21/05/21 | R 27 MFC Mykolaiv 1 FC VPK-Agro Shevchenkivka 0 G16:00 | 16/05/21 | R 26 PFC Nyva Ternopil 1 FC VPK-Agro Shevchenkivka 2 M17:00 | 12/05/21 | R 6 FC VPK-Agro Shevchenkivka 0 Veres Rivne 4 B17:00 | 07/05/21 | R 25 FC VPK-Agro Shevchenkivka 0 FC Polissya 0 |
| 12 | |  PFC Nyva Ternopil | 28 | 8 | 6 | 14 | 29 | 46 | -17 | 30 | G17:30 | 05/06/21 | R 29 PFC Nyva Ternopil 1 Agrobiznes Volochisk 0 M17:00 | 26/05/21 | R 28 MFC Mykolaiv 4 PFC Nyva Ternopil 0 G18:00 | 21/05/21 | R 27 PFC Nyva Ternopil 2 FC Polissya 0 M16:00 | 16/05/21 | R 26 PFC Nyva Ternopil 1 FC VPK-Agro Shevchenkivka 2 G15:30 | 07/05/21 | R 25 MFC Kremin Kremenchuk 1 PFC Nyva Ternopil 3 M15:00 | 30/04/21 | R 24 PFC Nyva Ternopil 0 FC Chornomorets Odessa 1 |
| 13 | |  FC Prykarpattya Ivano-Frankivsk | 28 | 8 | 6 | 14 | 23 | 40 | -17 | 30 | G17:30 | 05/06/21 | R 29 FC Prykarpattya Ivano-Frankivsk 2 Volyn Lutsk 0 G16:00 | 30/05/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Avangard Kramatorsk 1 M18:00 | 26/05/21 | R 28 FC Alians Lypova Dolyna 4 FC Prykarpattya Ivano-Frankivsk 1 M16:00 | 21/05/21 | R 27 FC Prykarpattya Ivano-Frankivsk 0 FC Metalist 1925 3 G15:00 | 16/05/21 | R 26 Krystal Kherson 0 FC Prykarpattya Ivano-Frankivsk 1 M17:00 | 12/05/21 | R 14 Volyn Lutsk 2 FC Prykarpattya Ivano-Frankivsk 0 |
| 14 | |  FC Avangard Kramatorsk | 29 | 8 | 5 | 16 | 29 | 50 | -21 | 29 | M16:00 | 05/06/21 | R 29 Veres Rivne 5 FC Avangard Kramatorsk 1 M16:00 | 30/05/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Avangard Kramatorsk 1 M17:00 | 26/05/21 | R 28 FC Avangard Kramatorsk 1 FC Obolon Kiev 2 G17:30 | 21/05/21 | R 27 FC Hirnyk-Sport Horishni Plavni 0 FC Avangard Kramatorsk 2 G17:00 | 16/05/21 | R 26 FC Polissya 1 FC Avangard Kramatorsk 2 G17:00 | 07/05/21 | R 25 FC Avangard Kramatorsk 2 Volyn Lutsk 1 |
| 15 | |  MFC Kremin Kremenchuk | 29 | 6 | 5 | 18 | 22 | 49 | -27 | 23 | M17:30 | 05/06/21 | R 29 MFC Kremin Kremenchuk 0 FC Metalist 1925 4 G17:00 | 26/05/21 | R 28 Krystal Kherson 1 MFC Kremin Kremenchuk 2 M17:00 | 21/05/21 | R 27 MFC Kremin Kremenchuk 0 Agrobiznes Volochisk 1 M17:00 | 15/05/21 | R 26 MFC Mykolaiv 2 MFC Kremin Kremenchuk 0 M15:30 | 07/05/21 | R 25 MFC Kremin Kremenchuk 1 PFC Nyva Ternopil 3 M16:00 | 30/04/21 | R 24 FC VPK-Agro Shevchenkivka 3 MFC Kremin Kremenchuk 0 |
| 16 | |  Krystal Kherson | 29 | 3 | 3 | 23 | 20 | 60 | -40 | 12 | G17:30 | 05/06/21 | R 29 FC VPK-Agro Shevchenkivka 1 Krystal Kherson 2 M17:00 | 26/05/21 | R 28 Krystal Kherson 1 MFC Kremin Kremenchuk 2 M19:00 | 21/05/21 | R 27 FC Chornomorets Odessa 4 Krystal Kherson 0 M15:00 | 16/05/21 | R 26 Krystal Kherson 0 FC Prykarpattya Ivano-Frankivsk 1 M16:00 | 07/05/21 | R 25 Veres Rivne 2 Krystal Kherson 0 G16:00 | 30/04/21 | R 24 Krystal Kherson 3 FC Obolon Kiev 2 |
