| 1 | |  FC Metalist Kharkiv | 20 | 17 | 2 | 1 | 52 | 9 | 43 | 53 | G18:30 | 29/11/21 | R 20  FC Obolon Kiev 1 FC Metalist Kharkiv 2 G19:45 | 20/11/21 | R 19 FC Metalist Kharkiv 3 FC Olimpik Donetsk 0 G18:45 | 13/11/21 | R 18 FC Metalist Kharkiv 4 FC Prykarpattya Ivano-Frankivsk 0 G15:15 | 07/11/21 | R 17 FC Uzhgorod 0 FC Metalist Kharkiv 2 G19:30 | 01/11/21 | R 16 FC Metalist Kharkiv 2 FC Alians Lypova Dolyna 0 G18:45 | 24/10/21 | R 15 FC Metalist Kharkiv 3 FC Podillya Khmelnytskyi 0 |
| 2 | |  FC Kryvbas Kriviy Rih | 20 | 12 | 6 | 2 | 38 | 17 | 21 | 42 | B16:30 | 28/11/21 | R 20 FC Kryvbas Kriviy Rih 1 Agrobiznes Volochisk 1 G18:45 | 21/11/21 | R 19 MFC Kremin Kremenchuk 0 FC Kryvbas Kriviy Rih 5 B14:15 | 14/11/21 | R 18 FC Kryvbas Kriviy Rih 0 Hirnyk-Sport Horishni Plavni 0 G18:30 | 05/11/21 | R 17 PFC Nyva Ternopil 1 FC Kryvbas Kriviy Rih 2 G13:15 | 30/10/21 | R 16 FC Olimpik Donetsk 0 FC Kryvbas Kriviy Rih 2 G15:30 | 23/10/21 | R 15 FC Polissya 1 FC Kryvbas Kriviy Rih 2 |
| 3 | |  FC Alians Lypova Dolyna | 19 | 10 | 3 | 6 | 33 | 24 | 9 | 33 | G14:15 | 29/11/21 | R 20 FC Kramatorsk 0 FC Alians Lypova Dolyna 2 B18:30 | 22/11/21 | R 19 FC Alians Lypova Dolyna 3 Vpk-Agro Shevchenkivka 3 M16:30 | 14/11/21 | R 18 Volyn Lutsk 1 FC Alians Lypova Dolyna 0 G19:30 | 08/11/21 | R 17 FC Alians Lypova Dolyna 3 FC Obolon Kiev 2 M19:30 | 01/11/21 | R 16 FC Metalist Kharkiv 2 FC Alians Lypova Dolyna 0 M13:15 | 23/10/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Alians Lypova Dolyna 1 |
| 4 | |  FC Obolon Kiev | 19 | 10 | 3 | 6 | 24 | 16 | 8 | 33 | M18:30 | 29/11/21 | R 20 FC Obolon Kiev 1 FC Metalist Kharkiv 2 G15:15 | 21/11/21 | R 19 FC Prykarpattya Ivano-Frankivsk 0 FC Obolon Kiev 2 M19:30 | 15/11/21 | R 18 FC Obolon Kiev 0 FC Uzhgorod 1 M19:30 | 08/11/21 | R 17 FC Alians Lypova Dolyna 3 FC Obolon Kiev 2 G18:45 | 31/10/21 | R 16 FC Obolon Kiev 1 FC Podillya Khmelnytskyi 0 G18:30 | 25/10/21 | R 15 FC Obolon Kiev 3 Agrobiznes Volochisk 1 |
| 5 | |  PFC Nyva Ternopil | 20 | 8 | 5 | 7 | 22 | 22 | 0 | 29 | G14:15 | 27/11/21 | R 20 PFC Nyva Ternopil 4 MFC Kremin Kremenchuk 2 G14:15 | 19/11/21 | R 19 Hirnyk-Sport Horishni Plavni 0 PFC Nyva Ternopil 2 G15:15 | 12/11/21 | R 18 FC Olimpik Donetsk 0 PFC Nyva Ternopil 1 M18:30 | 05/11/21 | R 17 PFC Nyva Ternopil 1 FC Kryvbas Kriviy Rih 2 B15:30 | 29/10/21 | R 16 FC Polissya 1 PFC Nyva Ternopil 1 M13:15 | 24/10/21 | R 15 FC Kramatorsk 2 PFC Nyva Ternopil 0 |
| 6 | |  Hirnyk-Sport Horishni Plavni | 20 | 8 | 5 | 7 | 15 | 17 | -2 | 29 | G14:15 | 26/11/21 | R 20 FC Olimpik Donetsk 0 Hirnyk-Sport Horishni Plavni 1 M14:15 | 19/11/21 | R 19 Hirnyk-Sport Horishni Plavni 0 PFC Nyva Ternopil 2 B14:15 | 14/11/21 | R 18 FC Kryvbas Kriviy Rih 0 Hirnyk-Sport Horishni Plavni 0 G14:15 | 07/11/21 | R 17 Hirnyk-Sport Horishni Plavni 1 FC Polissya 0 G14:15 | 31/10/21 | R 16 FC Kramatorsk 0 Hirnyk-Sport Horishni Plavni 1 G15:30 | 25/10/21 | R 15 Vpk-Agro Shevchenkivka 1 Hirnyk-Sport Horishni Plavni 2 |
| 7 | |  FC Prykarpattya Ivano-Frankivsk | 20 | 8 | 4 | 8 | 27 | 26 | 1 | 28 | M18:30 | 26/11/21 | R 20 Volyn Lutsk 2 FC Prykarpattya Ivano-Frankivsk 1 M15:15 | 21/11/21 | R 19 FC Prykarpattya Ivano-Frankivsk 0 FC Obolon Kiev 2 M18:45 | 13/11/21 | R 18 FC Metalist Kharkiv 4 FC Prykarpattya Ivano-Frankivsk 0 G15:15 | 06/11/21 | R 17 FC Prykarpattya Ivano-Frankivsk 2 FC Olimpik Donetsk 1 G15:30 | 30/10/21 | R 16 FC Prykarpattya Ivano-Frankivsk 3 FC Uzhgorod 1 G13:15 | 23/10/21 | R 15 FC Prykarpattya Ivano-Frankivsk 3 FC Alians Lypova Dolyna 1 |
| 8 | |  FC Podillya Khmelnytskyi | 20 | 7 | 5 | 8 | 19 | 18 | 1 | 26 | G15:15 | 27/11/21 | R 20 FC Polissya 1 FC Podillya Khmelnytskyi 2 G14:15 | 20/11/21 | R 19 FC Podillya Khmelnytskyi 2 FC Kramatorsk 1 M16:30 | 13/11/21 | R 18 Vpk-Agro Shevchenkivka 1 FC Podillya Khmelnytskyi 0 G15:15 | 08/11/21 | R 17 FC Podillya Khmelnytskyi 2 Volyn Lutsk 0 M18:45 | 31/10/21 | R 16 FC Obolon Kiev 1 FC Podillya Khmelnytskyi 0 M18:45 | 24/10/21 | R 15 FC Metalist Kharkiv 3 FC Podillya Khmelnytskyi 0 |
| 9 | |  MFC Mykolaiv | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| 9 | |  FC Polissya | 18 | 7 | 4 | 7 | 21 | 17 | 4 | 25 | M15:15 | 27/11/21 | R 20 FC Polissya 1 FC Podillya Khmelnytskyi 2 B14:15 | 22/11/21 | R 19 Agrobiznes Volochisk 0 FC Polissya 0 G15:15 | 17/11/21 | R 12 FC Polissya 3 Vpk-Agro Shevchenkivka 1 G14:15 | 13/11/21 | R 18 FC Polissya 2 MFC Kremin Kremenchuk 0 M14:15 | 07/11/21 | R 17 Hirnyk-Sport Horishni Plavni 1 FC Polissya 0 B18:30 | 03/11/21 | R 11 Volyn Lutsk 0 FC Polissya 0 |
| 10 | |  Volyn Lutsk | 19 | 6 | 7 | 6 | 17 | 20 | -3 | 25 | G18:30 | 26/11/21 | R 20 Volyn Lutsk 2 FC Prykarpattya Ivano-Frankivsk 1 M15:15 | 20/11/21 | R 19 FC Uzhgorod 1 Volyn Lutsk 0 G16:30 | 14/11/21 | R 18 Volyn Lutsk 1 FC Alians Lypova Dolyna 0 M15:15 | 08/11/21 | R 17 FC Podillya Khmelnytskyi 2 Volyn Lutsk 0 B18:30 | 03/11/21 | R 11 Volyn Lutsk 0 FC Polissya 0 M17:30 | 29/10/21 | R 16 Volyn Lutsk 0 Agrobiznes Volochisk 1 |
| 11 | |  FC Olimpik Donetsk | 19 | 7 | 2 | 10 | 19 | 23 | -4 | 23 | M14:15 | 26/11/21 | R 20 FC Olimpik Donetsk 0 Hirnyk-Sport Horishni Plavni 1 M19:45 | 20/11/21 | R 19 FC Metalist Kharkiv 3 FC Olimpik Donetsk 0 M15:15 | 12/11/21 | R 18 FC Olimpik Donetsk 0 PFC Nyva Ternopil 1 M15:15 | 06/11/21 | R 17 FC Prykarpattya Ivano-Frankivsk 2 FC Olimpik Donetsk 1 M13:15 | 30/10/21 | R 16 FC Olimpik Donetsk 0 FC Kryvbas Kriviy Rih 2 G15:30 | 24/10/21 | R 15 FC Uzhgorod 1 FC Olimpik Donetsk 3 |
| 12 | |  FC Kramatorsk | 18 | 7 | 1 | 10 | 16 | 24 | -8 | 22 | M14:15 | 29/11/21 | R 20 FC Kramatorsk 0 FC Alians Lypova Dolyna 2 M14:15 | 20/11/21 | R 19 FC Podillya Khmelnytskyi 2 FC Kramatorsk 1 B14:15 | 12/11/21 | R 18 FC Kramatorsk 1 Agrobiznes Volochisk 1 G14:15 | 06/11/21 | R 17 MFC Kremin Kremenchuk 0 FC Kramatorsk 1 M14:15 | 31/10/21 | R 16 FC Kramatorsk 0 Hirnyk-Sport Horishni Plavni 1 G13:15 | 24/10/21 | R 15 FC Kramatorsk 2 PFC Nyva Ternopil 0 |
| 13 | |  Agrobiznes Volochisk | 20 | 4 | 9 | 7 | 16 | 23 | -7 | 21 | B16:30 | 28/11/21 | R 20 FC Kryvbas Kriviy Rih 1 Agrobiznes Volochisk 1 B14:15 | 22/11/21 | R 19 Agrobiznes Volochisk 0 FC Polissya 0 B14:15 | 12/11/21 | R 18 FC Kramatorsk 1 Agrobiznes Volochisk 1 G15:15 | 05/11/21 | R 17 Agrobiznes Volochisk 1 Vpk-Agro Shevchenkivka 0 G17:30 | 29/10/21 | R 16 Volyn Lutsk 0 Agrobiznes Volochisk 1 M18:30 | 25/10/21 | R 15 FC Obolon Kiev 3 Agrobiznes Volochisk 1 |
| 14 | |  Vpk-Agro Shevchenkivka | 20 | 5 | 3 | 12 | 16 | 28 | -12 | 18 | B15:15 | 28/11/21 | R 20 Vpk-Agro Shevchenkivka 1 FC Uzhgorod 1 B18:30 | 22/11/21 | R 19 FC Alians Lypova Dolyna 3 Vpk-Agro Shevchenkivka 3 M15:15 | 17/11/21 | R 12 FC Polissya 3 Vpk-Agro Shevchenkivka 1 G16:30 | 13/11/21 | R 18 Vpk-Agro Shevchenkivka 1 FC Podillya Khmelnytskyi 0 M15:15 | 05/11/21 | R 17 Agrobiznes Volochisk 1 Vpk-Agro Shevchenkivka 0 G16:30 | 31/10/21 | R 16 Vpk-Agro Shevchenkivka 2 MFC Kremin Kremenchuk 0 |
| 15 | |  FC Uzhgorod | 20 | 4 | 4 | 12 | 16 | 40 | -24 | 16 | B15:15 | 28/11/21 | R 20 Vpk-Agro Shevchenkivka 1 FC Uzhgorod 1 G15:15 | 20/11/21 | R 19 FC Uzhgorod 1 Volyn Lutsk 0 G19:30 | 15/11/21 | R 18 FC Obolon Kiev 0 FC Uzhgorod 1 M15:15 | 07/11/21 | R 17 FC Uzhgorod 0 FC Metalist Kharkiv 2 M15:30 | 30/10/21 | R 16 FC Prykarpattya Ivano-Frankivsk 3 FC Uzhgorod 1 M15:30 | 24/10/21 | R 15 FC Uzhgorod 1 FC Olimpik Donetsk 3 |
| 16 | |  MFC Kremin Kremenchuk | 20 | 4 | 1 | 15 | 16 | 43 | -27 | 13 | M14:15 | 27/11/21 | R 20 PFC Nyva Ternopil 4 MFC Kremin Kremenchuk 2 M18:45 | 21/11/21 | R 19 MFC Kremin Kremenchuk 0 FC Kryvbas Kriviy Rih 5 M14:15 | 13/11/21 | R 18 FC Polissya 2 MFC Kremin Kremenchuk 0 M14:15 | 06/11/21 | R 17 MFC Kremin Kremenchuk 0 FC Kramatorsk 1 M16:30 | 31/10/21 | R 16 Vpk-Agro Shevchenkivka 2 MFC Kremin Kremenchuk 0 M17:30 | 22/10/21 | R 15 Volyn Lutsk 3 MFC Kremin Kremenchuk 2 |
